War on meat? A response to Sam Bailey on alpha-gal

There is much more going on than meets the eye.

War on meat? You’ve been fooled.

There is much more to this story than meets the eye. There is a geographical associated between reactions to eating meat and the lone star tic states.

‘Recent work has identified a novel IgE antibody response to the mammalian oligosaccharide epitope, α-gal, that has been associated with 2 distinct forms of anaphylaxis: (1) immediate-onset anaphylaxis during first exposure to intravenous cetuximab and (2) delayed-onset anaphylaxis 3 to 6 hours after ingestion of mammalian food products (eg, beef and pork)

‘The authors initially published the description of 24 cases of reactions to red meat and subsequently documented the serum IgE Ab levels in 208 cases. Currently they are aware of at least 1,000 cases in Virginia and have estimated that there must be several thousand more affected patients in the United States, because cases of meat-induced, delayed anaphylaxis have been reported in South Carolina, Texas, Georgia, Louisiana, Alabama, Mississippi, Kentucky, Oklahoma, Illinois, West Virginia, and Nebraska.’

‘The first clue to what causes or leads to the development of the IgE response to α-gal came from the observation that the area of the initial reactions to cetuximab coincided with the maximum prevalence of Rocky Mountain spotted fever. That observation led to questioning patients about tick bites, serial observations after tick bites, and serologic studies using extracts of ticks to investigate IgE antibodies. Taken together, the results provided strong evidence that bites from the lone star tick, Amblyomma americanum, were a cause of IgE Ab responses to α-gal in the United States.²⁵ Recent data have suggested an expanding range of A americanum, which is likely to increase the affected population (Fig 1). Interestingly, bites from the lone star tick are often severely pruritic and may persist for weeks.²⁵ In addition, the authors became aware that Van Nunen et al²² had reported to the Sydney Allergy Society that some people who were bitten by ticks in southern Australia had developed an allergy to meat.’

'Our study revealed an alarming frequency of (cetuximab) infusion-related HSR at the three sites examined, data that would call for a comprehensive survey of reactions in the middle southern US region that includes North and South Carolina, Tennessee, northern Georgia, and extends westward to Arkansas where HSR is also anecdotally problematic. The immediate and severe nature of these reactions suggests a pre-existing immunoglobulin E-based immune reaction directed at the antibody itself.’

The 22% of patients experiencing grade 3 to 4 HSR at UNC is significantly larger than the published percentage from the study by Cunningham et al of 1.2% (for the wider population not in lone star tic states).

It has been speculated but not proven that such a crossreactive response could be caused by increased exposure to mouse antigens or another antigen mimic of cetuximab that is regionally based, such as a particular plant or tree pollen.'

'Cetuximab is a drug that is used safely in most of the country, but we have identified several sites in the US middle south that have reaction rates much higher than reported nationwide. Investigation of the mechanism of this high rate of HSR is ongoing, but practitioners and patients in the region should be aware of the added risk of using cetuximab and take appropriate precautions.

So, the alpha gal theory was first put forward by noticing a 20 fold increase in severe reactions to monoclonal antibody cancer therapy in the same lone star tick states that seem to have delayed reactions to eating meat (when it crosses the gut barrier, and enters the blood stream rather than direct infusion).

The theory put forward for meat allergy was pre-exposure to alpha gal from animals via tick bites, the theory for Cetuximab allergy was pre-exposure to mouse antigens or particular plants or pollen in the lone star tick states, but not tick bites.

I don’t know why one is blamed on local pollen and the other on tick bites. They seem to be the same reaction.

A reaction in a person to a tick bite that had previously eaten a farmed animal, whose bodies make alpha-gal, which humans don’t, may be caused by the human recognising alpha-gal as a foreign substance and making a detox reaction. It wouldn’t happen every time as not every time would a tick have sucked blood from an animal before biting a human.

Maybe it’s actually in the dead flesh; from Northern Tracey, ‘I wonder how many people could be simply reacting to something IN the meat and don’t actually have anaphylaxis at all. What are they putting in the animals these days? mRNA? GMO’d feed? Multiple vaccines and antibiotics? The majority of animals bred for food are not bred at all. They very rarely actually let the animals do the dirty themselves no, they have complete control over what egg and sperm get together. Are they messing with that too? You betcha. Yes to all those things and more now. Maybe the meat itself is making people sick.’

The most important food reactions remain to shellfish, which may be due to the anisakid worm which causes inflammation alive or dead: eating chickens that have been fed fishmeal can even cause a reaction. Pig tapeworms, now becoming a western problem too due the increase in intensively farming animals, are the most common cause of epilepsy worldwide (tapeworms invade the brain).

If eating dead animals sometimes causes an ‘allergic’ reaction, whatever the ethology, it is best to avoid doing it. This is not a ‘war on meat’

Globalist agenda to stop us eating (very heavily tax-payer subsidised and widely advertised and promoted) dead animal flesh? No, follow the money. This is propaganda to increase demand and price.

🐒

The irony is that if they did want to our health and happiness to suffer by us not eating dead animals, it actually has the opposite effect.